Plague Inc. is a unique blend of high-level strategy and realistic simulation where your goal is to infect and wipe out the entire global population with a deadly pathogen. Developed by Ndemic Creations, the game puts you in the role of a virus creator, evolving your disease to overcome modern science, government actions, and global cooperation.
In version 1.21.0, Plague Inc. introduces new scenarios, disease types, and special events. The game challenges you to think critically about global systems while keeping you entertained with its deep gameplay mechanics and unpredictable outcomes. With millions of downloads and critical acclaim, Plague Inc. remains one of the most engaging strategy games on mobile.
In Plague Inc., your mission is to choose a starting country for your disease and begin infecting people. As your pathogen spreads, you’ll earn DNA points that you can use to evolve transmission methods, symptoms, and resistances. You’ll need to monitor how nations react, manage symptoms to avoid early detection, and balance lethality with infectivity to avoid killing your hosts too quickly. The world map is interactive and filled with data, giving you real-time feedback on your infection’s progress.
What are the best symptoms for Plague Inc?
The best symptoms depend on your strategy, but for a lethal combo, many players recommend using Coughing → Pneumonia → Pulmonary Fibrosis → Total Organ Failure. These cause high mortality once most of the world is infected. Adding Insomnia, Paranoia, or Seizures can slow down cure research too.
What are the best genes in Plague Inc?
Ideal gene setups vary, but a powerful combination includes ATP Boost (more DNA at start), Darwinist (evolves traits faster), Aquacyte or Teracyte (for hard-to-reach regions), Patho-Stasis (prevents symptom devolving), and Ionised Helix (gains DNA from devolving traits). These can greatly increase your chances of winning on higher difficulties.
What are the orange bubbles in Plague Inc?
Orange DNA bubbles appear during your plague’s evolution and give you bonus DNA points when tapped. They’re essential for funding further transmission, symptoms, and abilities, especially early in the game when DNA income is limited.
What are cheats in Plague Inc?
Cheats are unlockable gameplay modifiers that become available after you complete all standard plagues on Brutal difficulty. They include options like Unlimited DNA, Instant Evolution, No Cure Progress, and more, allowing for relaxed or chaotic gameplay experiments.
Can you play Plague Inc multiplayer on mobile?
Yes, Plague Inc includes a multiplayer mode called “Versus,” but it’s available in the Plague Inc: Evolved version, primarily on PC and consoles. The standard mobile version doesn’t support online multiplayer, though some fan-made modifications or unofficial apps might attempt to mimic this functionality.
What’s new in version 1.21.0?
The update includes performance enhancements, bug fixes, and a few quality-of-life improvements across various scenarios.